D165/10_MYOBATD II

DESCRPTION

The use of isolated tissues in the study of physiological and pharmacological function of organs has been performed for nearly a century. It is generally the mechanical properties of isolated tissues that interests us the most. However, the underlying electrical, biochemical (second messengers) and ionic (ion fluxes) alterations that mediate these responses are obviously important aspects of organ function. To a large extent, these properties can only be classified when specific tissues are studied in isolation.

In terms of in vitro techniques, characterization of many of the properties of isolated tissues (such as blood vessels) can occur at a number of different levels of organ integrity. WPI’s multichannel organ bath system is designed through years of research and development for simultaneous studies of isolated tissues in vitro. This easy-to-use, cost-effective bench-top system is suitable for experiments on vascular and non-vascular smooth muscle and cardiac muscle, for example, coronary artery, taenia coli, isolated atria and ventricle strips.