D125/154_PAP-8E

The PAP-8E is designed to support diagnoses of hemostasis disorders including von Willebrand Disease (vWD), Glanzmann’s disease, HIT, Bernard Soulier Syndrome, and Sticky Platelet Syndrome as well as to precisely monitor the use of anti-platelet drugs during clinical trials or patient therapy. (Aspirin, ReoPro®, Aggrenox®, Asasantin®, Pletal®, Plavix®, Persantine®, Integrelin®, Effient®, Ticlid).

The Platelet Aggregation Profiler, PAP-8E, is intended for usein clinical, research, university, biotechnology and pharmaceutical laboratories. The system measures the rate and extent of aggregation, agglutination, activation and inhibition reactions. Comprehensive results include area under the curve and area under the slope.

Clinical Laboratory

• Measure Ristocetin CoFactor
• Confirm diagnosis of HIT (Heparin Induced Thrombocytopenia)
• Evaluate and monitor patients with platelet funcion abnormalities
• Manage Anti-Platelet therapy
• Pre and post-operative support of LVAD patients
  (Left Ventricular    Assist Devices).

Pharmaceutical Laboratory

• Study Anti-Platelet compounds
• examine anti-infiammatory or other compounds
• Leukocyte aggregation and platelet-leukocyte interaction
• Microvolume capacity for discovery
• Pre-clinical or small animal model studies.

BioTechnology Laboratory 

• Measue activity and effectiveness of ricombination agents
• Study effects of engineered surfaces on platelet function
• Investigate dietary influences on platelet function.

Research laboratory

• Evaluate platelet-vascular interactions
• Examin anti-platelet and lytic agent effect in thrombotic models or events.

Veterinary Laboratory

• Measure Ristocetin CoFactor activity in canine
  and porcine species
• Study platelet function abnormalities in animals
• Measure platelet function
  in animal models.

Technical data